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Help Centre

Our help centre contains articles written by our support agents to help you.

Getting Started (4)


  • Using Coffalyser.Net to analyse MLPA data
  • Getting started with MLPA
  • Getting started with digitalMLPA
  • Workshops and Webinars
View 4 articles

Workshops & Webinars (7)


  • Workshop "MLPA – expert in a day"
  • How many different workshops does MRC Holland offer?
  • Workshops and Webinars
  • MLPA – virtual workshops
  • Webinars
View 7 articles

MLPA (46)


  • How do I add sheets to the sheet library in Coffalyser.Net?
  • How do I adjust a bin set (create a manual bin set) in Coffalyser.Net?
  • How do I add a CE device to Coffalyser.Net?
  • Video: How to perform SALSA MLPA data analysis for copy number determination in Coffalyser.Net
  • Video: How to analyse SALSA MS-MLPA data in Coffalyser.Net
View 46 articles

digitalMLPA (28)


  • Is it possible to detect point mutations with (digital)MLPA?
  • Is it possible to use SALSA (digital)MLPA probes on DNA derived from non-human organisms?
  • How can I confirm my (digital)MLPA results?
  • Getting started with digitalMLPA
  • Video: What is SALSA digitalMLPA?
View 28 articles

Melt Assays (4)


  • How should I store DNA samples?
  • How can I confirm results obtained with the MC002 SMA Newborn Screen?
  • What are the sample requirements for the MC002 SMA Newborn Screen?
  • Is a specific thermocycler required for the MC002 SMA Newborn Screen?
View 4 articles

Coffalyser.Net (49)


  • Using Coffalyser.Net to analyse MLPA data
  • How can I reset my Coffalyser.Net login password?
  • What keyboard shortcuts can I use in Coffalyser.Net?
  • How does Coffalyser.Net show results from mutation specific probes?
  • How do I add sheets to the sheet library in Coffalyser.Net?
View 49 articles

Coffalyser digitalMLPA (13)


  • What is the difference between Coffalyser.Net and Coffalyser digitalMLPA?
  • What are the Coffa (.coffa) files produced by Coffalyser digitalMLPA?
  • What are Coffalyser Definition Files (.cdf) used by Coffalyser digitalMLPA?
  • Coffalyser digitalMLPA User Manual
  • MRC Holland software is not affected by vulnerabilities in Log4j
View 13 articles

Product Information (6)


  • What do the product version numbers mean?
  • Where can I find the product descriptions for previous product versions?
  • What products are available?
  • What is the expiry date on SALSA (digital)MLPA reagents?
  • Where can I find the exact sequences recognised by SALSA (digital)MLPA probes?
View 6 articles

Ordering & Payment (7)


  • How can I order from MRC Holland?
  • What are the shipping and handling costs?
  • Do you have a distributor in my country?
  • Is it possible to obtain product samples?
  • Can I buy reagents separately?
View 7 articles

MRC Holland (6)


  • Can I have my samples tested at MRC Holland?
  • What does "SALSA" stand for?
  • Are there any license agreements or patents pertaining to MLPA?
  • What does MRC stand for?
  • Where is MRC Holland located?
View 6 articles

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