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  • How can I confirm results obtained with the MC002 SMA Newborn Screen?
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How can I confirm results obtained with the MC002 SMA Newborn Screen?

in Melt Assays
  • Melt Assay

Positive and ambiguous results obtained with the SALSA® MC002 SMA Newborn Screen must be confirmed or verified with SALSA® MLPA® Probemix P021 SMA (version B1 or later).

Use of the P021 SMA probemix allows the determination of the exon 7 copy number of both SMN1 and SMN2, and provides additional information that can help with result interpretation. This probemix can be used on DNA extracted from peripheral blood and on DNA extracted from washed DBS cards following protocol C in the MC002 instructions for use.

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Disclaimer

The information provided in this material is correct for the majority of our products. However, for certain applications, the instructions for use may differ. In the event of conflicting information, the relevant instructions for use take precedence.


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