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How many samples do I need to include in a digitalMLPA experiment with no dedicated reference samples?
The minimum number of samples required in a digitalMLPA™ experiment without dedicated reference samp...
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Do mismatches in probes influence (digital)MLPA results?
Probes can be affected by mismatches between the probe sequence and the sample DNA. The presence of ...
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Which Illumina reagent kits can be used for digitalMLPA?
Most Illumina Reagent Kits capable of generating 110 nt reads (single-end) are suitable for digitalM...
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Is the purity and quality of the sample DNA important for (digital)MLPA?
Sample purity is very important for conventional MLPA and digitalMLPA while sample quality is usuall...
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How many digitalMLPA samples can I combine in a single run?
You can calculate the maximum number of digitalMLPA samples that can be included in a single sequenc...
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Why is digitalMLPA more robust than conventional MLPA?
While conventional MLPA is already a highly robust technique for the detection of copy number change...
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Statement: No Safety Data Sheet Required
None of our products contain dangerous substances at concentrations that require the distribution of...
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Is there a specific DNA extraction method I need to use for (digital)MLPA samples?
No specific extraction method is required for conventional MLPA or digitalMLPA, as long as the DNA i...
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What is sample depurination and how do I prevent it?
To prevent sample depurination, it is essential that DNA samples contain sufficient buffering capaci...
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What Library Prep Kit do I select for digitalMLPA in the Illumina Local Run Manager?
When sequencing SALSA® digitalMLPA™ reactions, a run sheet must be prepared in the Local Run Manager...
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Is it possible to use DNA extracted from formalin-fixed paraffin-embedded (FFPE) tissue for (digital)MLPA?
It is possible to use DNA extracted from FFPE tissue for a limited number of conventional MLPA and d...