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Do I need special training to perform (digital)MLPA?
No special training is required to perform conventional MLPA or digitalMLPA experiments, as long as ...
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What are the Q- and D-fragments that are present in SALSA MLPA probemixes?
Q- and D-fragments are present in SALSA® MLPA® probemixes for quality evaluation of an MLPA experime...
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Do I need to purchase reagents separately?
SALSA® MLPA® and digitalMLPA™ reagents are supplied in reagent kits. These reagent kits contain all ...
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What can I do about impurities in my DNA sample?
To reduce the effect of impurities in a DNA sample on a conventional MLPA or digitalMLPA reaction, y...
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Is it possible to order a custom-designed (digital)MLPA probemix or to order part of a probemix?
It is not possible to order custom (digital)MLPA probes or probemixes from MRC Holland. However, we ...
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What are Binning DNA, Reference Selection DNA, and Artificial Duplication DNA for?
MRC Holland supplies three types of artificially made DNA samples: SALSA® Binning DNA, SALSA® Refere...
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Do mismatches in probes influence (digital)MLPA results?
Probes can be affected by mismatches between the probe sequence and the sample DNA. The presence of ...
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Is the purity and quality of the sample DNA important for (digital)MLPA?
Sample purity is very important for conventional MLPA and digitalMLPA while sample quality is usuall...
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Can I use the Promega Spectrum Compact or Hitachi DS3000 for MLPA with Coffalyser.Net?
It is possible to use the Promega Spectrum Compact or Hitachi Compact CE Sequencer DS3000 for MLPA. ...
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Statement: No Safety Data Sheet Required
None of our products contain dangerous substances at concentrations that require the distribution of...
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Is there a specific DNA extraction method I need to use for (digital)MLPA samples?
No specific extraction method is required for conventional MLPA or digitalMLPA, as long as the DNA i...
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What is sample depurination and how do I prevent it?
To prevent sample depurination, it is essential that DNA samples contain sufficient buffering capaci...