It is not possible to install Coffalyser.Net or Coffalyser digitalMLPA on macOS (Mac OS X) or Linux.
Background
Both programs runs on the Microsoft .NET Framework, which means that they are dependent on the Windows operating system. However, it is possible to run Windows programs on macOS or Linux systems via a virtual machine that runs Windows. For more details, see the system requirements of Coffalyser.Net or Coffalyser digitalMLPA.