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  • Brochure: General digitalMLPA Information

Brochure: General digitalMLPA Information

  • digitalMLPA
General-digitalMLPA-Information-GB-DM-G-004D.pdf (4.04 MB)

SALSA® digital Multiplex Ligation-dependent Probe Amplification (digitalMLPA™) is a multiplex PCR followed by Illumina sequencing-based amplicon quantification, for the detection of copy number variations (CNV) and specific point mutations. digitalMLPA amplifies ligated probes with a universal primer pair enabling unbiased amplification. With digitalMLPA, up to 1000 unique sequences can be detected and quantified in a single reaction.

The digitalMLPA technique is similar to conventional MLPA®, the gold standard for CNV detection of multiple DNA sequences, but with the ability to examine many more targets in a single reaction. digitalMLPA samples can be combined with other NGS sequencing libraries in a single run to give simultaneous results for reliable CNV quantification and NGS sequence analysis. This saves time and money, ensuring sample result turnaround times are met.

This brochure provides an overview of the digitalMLPA technique. More information about our products can be found in one of our application-specific brochures, via our assay finder, or in our full product catalogue.

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Related Files

  • Flyer: MS-MLPA
  • Flyer: SALSA digitalMLPA Probemix D001 Hereditary Cancer Panel 1
  • Brochure: General MLPA Information

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Disclaimer

The information provided in this material is correct for the majority of our products. However, for certain applications, the instructions for use may differ. In the event of conflicting information, the relevant instructions for use take precedence.


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