SALSA^® digitalMLPA™ is a multiplex PCR followed by Illumina sequencing-based amplicon quantification, for the detection of copy number variations (CNV) and specific single nucleotide variants (SNV). digitalMLPA amplifies ligated probes with a universal primer pair, enabling unbiased amplification. With digitalMLPA, up to 1000 unique sequences can be detected and quantified in a single reaction.

The digitalMLPA technique is similar to SALSA^® MLPA^®, the gold standard for CNV detection, but with the ability to examine many more targets in a single reaction.

Analysis is done using free, easy-to-use software – so no bioinformatic skills are needed.

This brochure provides an overview of the digitalMLPA technique. More information about our products can be found in one of our application-specific brochures, via our assay finder, or in our full price list.