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Is it possible to use SALSA (digital)MLPA probes on DNA derived from non-human organisms? - Help Centre / MLPA & Coffalyser.Net / MLPA Technique - MRC Holland Support

Is it possible to use SALSA (digital)MLPA probes on DNA derived from non-human organisms?

No, it is not possible to use SALSA® MLPA® or SALSA® digitalMLPA™ products on non-human derived DNA. It is very likely that one or more mismatches exist in other organisms. These mismatches are likely to disrupt the probe's ligation or its hybridization to the sample DNA. 

MLPA can, in principle, be applied to DNA derived from other organisms, but we offer no support for this.

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The information provided in this material is correct for the majority of our products. For certain applications, the instructions for use may differ. In the event of conflicting information, the relevant instructions for use take precedence.