115 search results for "MLPA"
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What is sample depurination and how do I prevent it?
To prevent sample depurination, it is essential that DNA samples contain sufficient buffering capaci...
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What electrophoresis devices can I use for MLPA fragment analysis?
The MLPA procedure includes the separation of MLPA fragments on a capillary electrophoresis device. ...
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Is it possible to use DNA extracted from formalin-fixed paraffin-embedded (FFPE) tissue for (digital)MLPA?
It is possible to use DNA extracted from FFPE tissue for a limited number of conventional MLPA and d...
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What are the sample and buffer requirements for (digital)MLPA?
The main sample requirements for MLPA and digitalMLPA are listed below. NoteThe instructions for ind...
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Which factors influence variability of (digital)MLPA probes?
Variability in conventional MLPA and digitalMLPA experiments can be introduced by several factors, i...
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What is MLPA, and how does it work?
MLPA (Multiplex Ligation-dependent Probe Amplification) is a method that detects aberrant copy numbe...
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Ethanol precipitation protocol
DNA precipitation by ethanol can be used to concentrate highly diluted DNA samples and to remove cer...
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What do the product version numbers mean?
We use version numbers to make sure that changes to a product are noticed by our customers. Our vers...
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MLPA General Protocol
Published online on 26 May 2025. This is the latest MLPA General Protocol. The MLPA General Protoco...
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What are the main advantages and limitations of MLPA?
Advantages The main advantages of MLPA are that it is a high throughput and cost effective way to c...
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What is the optimal signal range for capillary electrophoresis of MLPA fragments?
The optimal signal range for MLPA fragment peaks depends on the electrophoresis device. Care should ...
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How can I anonymise MLPA data before sending it to MRC Holland?
It may sometimes be necessary or useful to share raw MLPA data files from capillary electrophoresis ...